AUTHOREA
Log in Sign Up Browse Preprints

loading page

Modular, Scalable Total Synthesis of Neopetromin
  • Hiroshige Ogawa,
  • Yuuya Nagata,
  • Hugh Nakamura
Hiroshige Ogawa
The Hong Kong University of Science and Technology
Author Profile
Yuuya Nagata
Hokkaido University
Author Profile
Hugh Nakamura
The Hong Kong University of Science and Technology

Corresponding Author:hnakamura@ust.hk

Author Profile

Abstract

The first total synthesis of neopetromin, featuring the highly strained Tyr C-6-to-Trp N-1′ linkage, is hereby reported. This modular synthetic strategy, employing C-H biarylation and Larock macrocyclization, offers a novel approach to the synthesis of various RiPPs natural product families.

Peer review status:ACCEPTED

Submitted to Chinese Journal of Chemistry
Show details
Hide details
Submission Checks Completed
Assigned to Editor
Reviewer(s) Assigned
16 Jul 2024Review(s) Completed, Editorial Evaluation Pending
18 Jul 2024Editorial Decision: Revise Minor
31 Jul 20241st Revision Received
02 Aug 2024Submission Checks Completed
02 Aug 2024Assigned to Editor
02 Aug 2024Review(s) Completed, Editorial Evaluation Pending
02 Aug 2024Editorial Decision: Accept