Abstract
Exosomes are nanoscale membrane vesicles identified by electron
microscopy in 1946. They are approximately 30-150 nanometers in size.
Originally, exosomes were thought to be used to eliminate excess
components from cells to maintain their normal physiology. In recent
years, studies have shown that the function and targeting of specific
cellular components in exosomes have important implications for the
regulation of cellular communication. In the last few years, exosomes
have been implicated in oncology, infections and other diseases and have
been shown to have an impact on cancer progression. New advances in
cancer immunotherapy have occurred as a result of the identification of
Exosomes of immune cell origin, expanding the existing anti-cancer
immune response. This paper details exosomes derived from dendritic
cells, T-lymphocytes (CD4+ T-cells, CD8+ T-cells, CAR-T-cells), natural
killer cells and their promising applications in tumor therapy.