Conclusion:
Pituitary lesions (mass/hyperplasia) on radiological findings can have different interpretations. A systematic investigation combining biochemical, clinical, and radiological evidence is essential before initiating therapy. This approach helps prevent unnecessary surgical interventions and avoids delays in necessary surgical treatments. Not every pituitary mass represents an adenoma, particularly a prolactinoma; hyperplasia or other types of pituitary cell adenomas should always be considered as differential diagnoses. Although rare, TSHoma do exist, distinguishing them from thyroid hormone resistance can be challenging. In conclusion, a thorough, multi-faceted approach to diagnosing pituitary lesions is essential for ensuring accurate treatment and optimal patient outcomes .