Introduction:
Felty syndrome, also known as Chauffard-Still-Felty syndrome, was first
described by Augustus Felty. It is a rare condition diagnosed in
patients with longstanding seropositive rheumatoid arthritis (RA)
characterized by an enlarged spleen and neutropenia (1). Neutropenia,
defined as absolute neutrophil count <1500/mm, is Felty
syndrome’s hallmark feature. In RA, the patient usually presents
initially with arthritis, and the felty syndrome commonly develops after
many years. However, in highly uncommon instances, felty syndrome can
manifest before or without any signs of arthritis. Only a few case
reports have been published highlighting this unusual presentation of
the Felty syndrome (Table 2). We present a similar case of a young
female who initially presented with felty syndrome without arthritis.
This case report emphasizes the clinical and diagnostic approach to rule
out alternate causes of neutropenia with splenomegaly and timely
recognition of the atypical presentation of Felty syndrome.