Case presentation:
A 29-year-old female presented to the Obstetrics and Gynecology Department with a sudden stop in pregnancy symptoms such as pregnancy craving, vomiting and nausea, accompanied by pain in the lower abdomen and mild bloody mottling. There were no other symptoms. The patient had a partus caesarius two years ago. Our patient has smoked 3 packs\year for 6 years. There was no other medical, family, surgical, or allergic history. The pregnancy age depends on the last menstrual cycle was 12 weeks +2 days. The patient had never had a US before. The US demonstrated a dead fetus inside the uterus at age 11 weeks with irregularities in the skull bones and severe cerebral malformation. A single orbital cave is also noted. The US investigation was ineffective. 800 mg of Misoprostol was prescribed to induce medical miscarriage (400 mg oral and 400 mg vaginal). The pathological exam demonstrated a male embryo measuring 7 cm in length (Fig. 1). Gross examination showed a single central orbit located in the middle of the face with a cutaneous horn above it (Fig. 2); and polydactyly in its foot, attached with a normal umbilical cord (Fig. 3). The visceral organs of the embryo were normal except the brain’s front, which showed adhesion of its right and left hemispheres. A placenta measures 7 x 2 cm and is composed of normal villi and decidual tissue (Fig. 1).