The conflicting domains is a serious problem in problem frame diagram. These conflicting domains need to be identified and removed. Purpose: The purpose of the paper is to find the conflicting domains, categorize them, and annotate them on real world case study. Design/methodology/approach: This paper takes the three categories of conflicts such as inconsistencies, inclusion, and interlock to find the conflicting domains. Finding: the results show us the different annotation or symbols to represents these conflicting domains. Based on the annotations or symbols you can say there is a possibility of conflicts between these domains. Conclusion: This paper provide us the annotations or symbols such as interdependenacy, inclusion, and interlock to represent the conflict between domains in insulin injection control system and regular monitoring of patient case studies. Originality/value: The paper addresses a gap of conflicting domains and their annotations or symbols to represent it, is acknowledged both in the literature and by practitioners.