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Population pharmacokinetic-pharmacodynamic model of subcutaneous bupivacaine in a novel extended-release microparticle formulation

Ida Klitzing Storgaard, M.Sc.,¹ Elisabeth Kjær Jensen, M.D.,^2,3 Søren Bøgevig, M.D., Ph.D.,⁴ Torben Balchen, M.Sc.,³Anders Holten Springborg, M.D.,^2,3 Mike Allan Royal, M.D., J.D.,⁵ Kirsten Møller, M.D., Ph.D.,^6,7 Mads Utke Werner M.D., Ph.D.,^2,3,8 and Trine Meldgaard Lund, M.Sc., Ph.D.¹