2.3 Etiological Detection
Of all the 465 cases, 223(47.96%) had been taken specimen and tested, ALL negative for SARS-COV-2 and influenza, of which, 89 (39.91%) were tested positive for HRV without genotyping.
2.5 ClinicalCharacteristics of the patients in the outbreaks
We collected all the core health indicators of the enrolled patients, such as age, sex, the temperature of the patients, and the symptoms of the patients: cough, sore throat, muscle pain, headache, conjunctival congestion, runny nose, sneeze, diarrhea and vomit.
We analyzed and found the average age of all the patients is 11.9±5.9 years, and the median age is 10. A total of 290 males and 175 females were enrolled, 344/465 (73.98%) had a record of temperature over than 37.3 ℃, 138/465 (29.68%) had runny nose, 139/465 (29.89%) had sore throat, 86/465 (18.49%) had cough, 41/465 (8.82%) had headache, 37/465 (7.96%) had sneeze, and we found the female patients had a higher rate of have fever and more likely to be tested positive for the HRV test (Table 2 ). Notably, 7/465 (1.51%) had muscle pain, 5/465 (1.08%) had diarrhea, 1/465 (0.22%) had conjunctival congestion, and 1/465 (0.22%) had vomit.
We next analyzed the results by age group, and found the patients less than 5 years old had the highest rate of have fever, and if the patients had an elder age will have less rate of have fever, but the patients over than 18 had the opposite trend. The patients at the age of 9 to 10 had the highest rate of have cough. Patients at the age of 13 to 15 had the highest rate of sore throat and runny nose, patients at the age of 11 to 12 had the highest rate of sneeze, and patients at age of 12 to 14 had the highest rate of positive rate (Table 3 ).
We next found that the tested patients had a statistical lower rate of fever than that of the patients without test (χ2 =32.563, P <0.001), that might be due to our preference to take specimens of the cases with symptoms such as fever during field investigations. The rest of the clinical characteristics were no statistical difference between the tested and not tested ones (Table 4 ).