Aim: The purpose of this study was to investigate whether/how digital media exposure influences people’s intention to influenza vaccination. Subject and Methods: Through an anonymous online survey, we collected data on Chinese people’s exposure to influenza and influenza vaccine information on digital media platforms and their attitudes toward influenza vaccines(N=600). The structural equation model analysis results lent strong support to the research hypotheses and the proposed model. Results: The findings reveal three major themes: (1) digital media exposure has a significant influence on the susceptibility and severity of influenza. (2) After total exposure to digital media, it is helpful to understand the benefits of the vaccine, reduce the barriers to vaccination, and finally improve the intention to vaccination. (3) Users receive cues to action from digital media, and their vaccination intention tends to be positive. These findings explore how digital media exposure influences influenza vaccination intention and may provide insights into vaccine promotion efforts in countries. Conclusion: Research has shown that digital media exposure contributes to getting vaccinated against influenza.