Characteristics
during COVID-19 pandemic (2019.12.1-2020.11.30)
before COVID-19 pandemic (2018.12.1-2019.11.30)
P value
Total No. 1510 1750
Age(y), mean±SD 61.9±12.3 60.5±12.5 0.001
Age <0.001
<60 625(41) 828(47)
≥60 885(59) 922(53)
Gender 0.002
Male 868(57) 1098(63)
Female 642(43) 652(37)
Residence
Rural 850(56) 930(53) 0.066
Urban 639(42) 797(46)
Unknow 21(1) 23(1)
Smoke history 0.001
Yes 424(28) 584(34)
No 1081(72) 1159(66)
Unknown 5(0) 7(0)
Alcohol history 0.017
Yes 346(23) 464(27)
No 1159(77) 1279(73)
Unknown 5(0) 7(0)
Comorbidities
Ischemic heart disease 62(4) 53(3) 0.096
Ischemic stroke 156(10) 150(9) 0.086
Hypertension 970(64) 1141(65) 0.567
Diabetes 137(9) 143(8) 0.360
Pre-ICH anti-hypertension† 281/970(29) 299/1141(26) 0.156
Pre ACEI/ARB usage 49/281(17) 45/299(15) 0.436
Vehicle to hospital <0.001
Ambulance 660(44) 1012(58)
Self-admission 838(55) 686(39)
Unknown 12(1) 52(3)
Duration from onset to admission(h), M (P25, P75) 4(2,12) 6(2,24) <0.001
Systolic‐BP on admission (mm Hg), M(P25, P75) 171.3±29.2 164.3±28.7 <0.001
Diastolic-BP on admission (mm Hg), mean±SD 97.6±16.9 95.7±17.6 0.002
NIHSS on admission, M(P25, P75) 11.6±10.5 10.8±10.0 0.039
Location of hematoma, n(%) 0.010*
Lobe 292(19) 403(23)
Deep 1218(81) 1347(77)
Hematoma volume(ml), M(P25, P75) ‡ 11.0(5.0,27.0) 10.0(4.6,20.9) 0.009*
IVH, n (%) 249(16) 238(14) 0.021*
ICU treatment, n(%) 960(64) 938(54) <0.001*
Surgical intervention, n(%) 271(18) 358(20) 0.269
SMASH-U classification
Structural lesion 26(2) 31(2) 0.914
Medication 7(0) 4(0) 0.365
Amyloid angiopathy 196(13) 235(13) 0.706
Systemic Diseases 16(1) 18(1) 0.931
Hypertension 775(51) 919(53) 0.498
Undetermined 411(27) 478(27) 0.951
Laboratory measurements on admission
TC (mmol/L), mean±SD 4.6±1.5 4.7±3.0 0.577
Triglycerides(mmol/L), mean±SD 1.7±2.7 1.7±3.9 0.851
LDL‐C(mmol/L), mean±SD 2.6±0.8 2.6±0.9 0.833
PT(s), M(P25, P75) 12.4±4.8 12.8±6.2 0.068
INR, mean±SD 1.0±0.2 1.1±0.6 0.136
APTT(s), mean±SD 29.1±11.4 30.1±11.7 0.013
FIB(g/L), M(P25, P75) 2.9(2.4,3.6) 3.0(2.4,3.8) 0.001
Platelet count (×109/L), mean±SD 196.3±65.6 195.8±68.7 0.826
Fasting blood glucose (mmol/L), M(P25, P75)
6.2(5.2,7.8)
6.1(5.3,7.3)
0.003