Effects of the 52% low-sodium salt applied to CM-DASH diet in
hypertensive patients with type 2 diabetes:A Randomized Controlled
Trial
Abstract
Background and Aims: The DASH diet have been proven to be effective in
lowering blood pressure (BP), but it is rarely used in people with type
2 diabetes (T2D), especially in the Chinese population. We aimed to
evaluate the effects of 52% low- sodium salt applied to CM-DASH diet in
patients with hypertension and T2D. Methods and Results: This trial is a
single-blind, randomized controlled study conducted from December 2019
to November 2020 at Chongqing, China. 61 participants were randomly
allocated to intervention group or control group for 8 weeks.2
participants were lost, and 59 patients were finally included in the
analysis. The systolic blood pressure (SBP) and diastolic blood pressure
(DBP) of intervention group and control group were significantly
decreased compared with baseline, but there was no difference between
groups. The 24-hour urine Na+ and Cl- of the two groups decreased
significantly after intervention, but the increase of 24-hour urine K+
and the decrease of Na+/ K+ ratio were only observed in the intervention
group. Furthermore,the urine urinary albumin creatinine ratio (UACR) and
serum creatinine of two groups also decreased from baseline.
Conclusions: Following the CM-DASH diet in hypertensive patients with
T2D has beneficial effects in improving SBP and DBP. and the application
of 52% low-sodium salt has a significant effect in reducing sodium
intake and increasing potassium intake.