GULİN FINDIKOGLU

and 5 more

Objective: The aim of this study is to investigate the several physical, cognitive and metabolic factors effecting the gait speed in individuals with type 2 diabetes mellitus (T2DM) without neuropathy. Patients and Methods: This is a cross-sectional study. Seventy-one diabetic individuals were questioned for clinical symtomps of neuropathy and screened with DN4. The mean age of the participants was 55.87±7.74 years and M/F ratio was 14.1/85.9 %. Participants were grouped as slow walkers (SW) and average or brisk walkers (ABW) with a cut-off point of 1 m/s. The groups were compared with age, sex, body mass index (BMI), HbA1c level, fasting glucose, systolic blood pressure, VO2max, percent of muscle mass, percent of lower extremity muscle mass, Mini-Mental State Examination (MMSE) score and the year of education. A multivariate regression analysis was made to explain the effects of these factors on the gait speed. Results: VO2max (14.49 ± 2.95 vs 16.25 ± 2.94), MMSE (25.01 ± 3.21 vs 27.35 ± 1.97), year of education and sex were significantly different between SW and ABW (p<0.05). Age, sex, and year of education were considered as confounding factors. Among models the combination of factors VO2max, sex, MMSE Score, fasting glucose, systolic blood pressure explained only 24.1 % of the gait speed. MMSE score and VO2max were significantly related to the gait speed. Conclusion: VO2max and MMSE were significantly lower in SW and were independent determinants for the gait speed in diabetic people without neuropathy.