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Ting  Liu
Ting Liu

Public Documents 1
Electrochemical dearomative spirocyclization of N-acyl sulfona-mides in a continuous-...
Ting  Liu
Zhaojiang  Shi

Ting Liu

and 4 more

January 30, 2024
The development of efficient and sustainable methods to obtain spirocyclic compounds is of significance as these structures are widely found in pharmaceuticals and agrochemicals. Herein, we disclose an electrochemical dearomative spirocyclization of N-acyl sulfonamides in a continuous-flow cell. The reaction is simple and efficient without external catalysts or supporting electrolytes, in-cluding a decagram-scale synthesis.

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