Conclusion
There was adequate knowledge about gout and management among patients.
Knowledge, patient age, and management of gout had significant
associations with gout status among these patients. Most of the patients
had been diagnosed between the ages of 25 and 44 years. Patients’ chief
complaints at the time of diagnosis had no associations with their gout
statuses.
Conflict of Interest
Authors reported no conflict of interest.
Funding
The authors extend their appreciation to the deputyship for Research and
innovation, Ministry of education in Saudi Arabia for funding this
research work through the project number (IF-PSAU- 2021/03/17631)
Ethical Approval
This research had ethical approval from Prince Sattam bin Abdulaziz
University Deanship of Scientific Research, Research Ethics committee in
Health and Science Disciplines. Approval number (REC-HSD-99-2021)
Authors Contribution
AAK conceived and designed the study, conducted research, provided
research materials, and commenced at writing initial and final draft of
the article. AAB, AMM, AMA, RAA, ASA, TDA, NAA , AAA collected ,
organized , analyzed and interpreted data. Also, they provided logistic
support. ALL authors have critically reviewed and approved the final
draft and are responsible for the content and similarity index of the
manuscript.
Ragab, G., Elshahaly, M., & Bardin, T. (2017). Gout: An old disease
in new perspective - A review. Journal of Advanced Research,
8 (5), 495–511.https://doi.org/10.1016/j.jare.2017.04.008
Pascart, T., & Lioté, F. (2019). Gout: State of the art after a
decade of developments.
Rheumatology (Oxford, England), 58(1), 27–44.https://doi.org/10.1093/rheumatology/key002
- Wu, M., Tian, Y., Wang, Q., & Guo, C. (2020). Gout: a disease
involved with complicated immunoinflammatory responses: a narrative
review. Clinical Rheumatology, 39 (10), 2849–2859.https://doi.org/10.1007/s10067-020-05090-8
- Bao, W., Xue, Y., Cheng, X., Wang, P., Yin, B., Su, Y., & Jia, C.
(2022). Gout-associated uric acid crystals induce tophi ulcerations
and impair wound healing in a novel gouty ulcer model. Wound
Repair and Regeneration, 30 (1), 132–139.https://doi.org/10.1111/wrr.12973
- Kanwal, A., Abida, L., Sana, A., & Ahlam S. (2018). A systematic
review on the prevalence, pathophysiology, diagnosis, management, and
treatment of gout (2007-2018). GSC Biological and Pharmaceutical
Sciences , 5(1), 050–055.https://doi.org/10.30574/gscbps.2018.5.1.0077
- Kuo, C. F., Grainge, M. J., Zhang, W., & Doherty, M. (2015). Global
epidemiology of gout: Prevalence, incidence and risk factors.Nature Reviews. Rheumatology, 11 (11), 649–662.https://doi.org/10.1038/nrrheum.2015.91
- Smith, E. U., Díaz-Torné, C., Perez-Ruiz, F., & March, L. M. (2010).
Epidemiology of gout: An update. Best Practice & Research.
Clinical Rheumatology, 24 (6), 811–827.https://doi.org/10.1016/j.berh.2010.10.004
- Xia, Y., Wu, Q., Wang, H., Zhang, S., Jiang, Y., Gong, T., Xu, X.,
Chang, Q., Niu, K., & Zhao, Y. (2020). Global, regional and national
burden of gout, 1990-2017: A systematic analysis of the Global Burden
of Disease Study. Rheumatology (Oxford, England), 59 (7),
1529–1538.https://doi.org/10.1093/rheumatology/kez476
- Spaetgens, B., Pustjens, T., Scheepers, L. E. J. M., Janssens, H. J.
E. M., van der Linden, S., & Boonen, A. (2016). Knowledge, illness
perceptions and stated clinical practice behaviour in management of
gout: A mixed methods study in general practice. Clinical
Rheumatology, 35 (8), 2053–2061.https://doi.org/10.1007/s10067-016-3212-2
- Richette, P., Doherty, M., Pascual, E., Barskova, V., Becce, F.,
Castaneda, J., Coyfish, M., Guillo, S., Jansen, T., Janssens, H.,
Lioté, F., Mallen, C. D., Nuki, G., Perez-Ruiz, F., Pimentao, J.,
Punzi, L., Pywell, A., So, A. K., Tausche, A. K., . . . Bardin, T.
(2020). 2018 updated European League Against Rheumatism evidence-based
recommendations for the diagnosis of gout. Annals of the
Rheumatic Diseases, 79 (1), 31–38.https://doi.org/10.1136/annrheumdis-2019-215315
- Gaffo, A. L., Dalbeth, N., Saag, K. G., Singh, J. A., Rahn, E. J.,
Mudano, A. S., Chen, Y. H., Lin, C. T., Bourke, S., Louthrenoo, W.,
Vazquez-Mellado, J., Hernández-Llinas, H., Neogi, T., Vargas-Santos,
A. B., da Rocha Castelar-Pinheiro, G., Amorim, R. B. C., Uhlig, T.,
Hammer, H. B., Eliseev, M., . . . Taylor, W. (2018). Brief Report:
Validation of a Definition of Flare in Patients With Established Gout.Arthritis & Rheumatology (Hoboken, N.J.), 70 (3), 462–467.https://doi.org/10.1002/art.40381
- Singh, J. A. (2014). The impact of gout on patient’s lives: a study of
African-American and Caucasian men and women with gout.Arthritis Research & Therapy ,16(3), R132.https://doi.org/10.1186/ar4589
- Jin, J., Sklar, G. E., Min Sen Oh, V., & Chuen Li, S. (2008). Factors
affecting therapeutic compliance: A review from the patient’s
perspective. Therapeutics and Clinical Risk Management, 4 (1),
269–286.https://doi.org/10.2147/TCRM.S1458
- Moi, J. H., Sriranganathan, M. K., Edwards, C. J., & Buchbinder, R.
(2013). Lifestyle interventions for chronic gout. Cochrane
Database of Systematic Reviews , 2013(5), CD010039.https://doi.org/10.1002/14651858.CD010039.pub2
- Singh, J. A. (2009). Quality of life and quality of care for patients
with gout. Current Rheumatology Reports, 11 (2), 154–160.https://doi.org/10.1007/s11926-009-0022-4
- Pascal T, Lioté F. Gout: state of the art after a decade of
developments. Rheumatol. 2019; 58(1):27-44. doi:
10.1093/rheumatology/key002
- Wu M, Tian Y, Wang Q, Guo C. Gout: a disease involved with complicated
immunoinflammatory responses: a narrative review. Clin Rheumatol.
2020; 39(10):2849-2859. doi: 10.1007/s10067-020-05090-8
- Bao W, Xue Y, Cheng X, Wang P, Yin B, Su Y, et al. Gout associated
uric acid crystals induce tophi ulcerations and impair wound healing
in a novel gouty ulcer model. Wound Repair Regen. 2022;30(1):132-139.
doi: 10.1111/wrr.12973
- Kuo CF, Grainge MJ, Zhang W, Doherty M. Global epidemiology of gout:
prevalence, incidence and risk factors. Nat Rev Rheumatol.
2015;11(11):649-662. doi: 10.1038/nrrheum.2015.91
- Smith EU, Diaz-Torne C, Perez-Ruiz F, March LM. Epidemiology of gout:
an update. Best Pract Res Clin Rheumatol. 2010;24(6):811-827. doi:
10.1016/j.berh.2010.10.004
- Xia Y, Wu Q, Wang H, Zhang S, Jiang Y, Gong T, et al. Global, regional
and national burden of gout, 1990–2017: a systematic analysis of the
Global Burden of Disease Study. Rheumatol. 2020;59(7):1529-1538. doi:
10.1093/rheumatology/kez476
- Spaetgens B, Pustjens T, Scheepers LEJM, Janssens HJEM, van der Linden
S, Boonen A. Knowledge, illness perceptions and stated clinical
practice behaviour in management of gout: a mixed methods study in
general practice. Clin Rheumatol. 2016;35(8):2053-2061.
doi:10.1007/s10067-016-3212-2
- Richette P, Doherty M, Pascual E, et al. 2018 updated European League
Against Rheumatism evidence-based recommendations for the diagnosis of
gout. Ann Rheum Dis. 2020;79(1):31-38.
doi:10.1136/annrheumdis-2019-215315
- Gaffo AL, Dalbeth N, Saag KG, et al. Brief Report: Validation of a
Definition of Flare in Patients With Established Gout. Arthritis
Rheumatol. 2018;70(3):462-467. doi:10.1002/art.40381 14 Singh JA. The
impact of gout on patient’s lives: a study of African-American and
Caucasian men and women with gout. Arthritis Res Ther.
2014;16(3):R132. Published 2014 Jun 24. doi:10.1186/ar4589
15 Jin J, Sklar GE, Min Sen Oh V, Chuen Li S. Factors affecting
therapeutic compliance: A review from the patient’s perspective. Ther
Clin Risk Manag. 2008;4(1):269-286. doi:10.2147/tcrm.s1458 16 Moi JH,
Sriranganathan MK, Edwards CJ, Buchbinder R. Lifestyle interventions for
chronic gout. Cochrane Database Syst Rev. 2013;2013(5):CD010039.
Published 2013 May 31. doi:10.1002/14651858.CD010039.pub2
17 Singh J. A. (2009). Quality of life and quality of care for patients
with gout. Current rheumatology reports, 11(2), 154–160.
https://doi.org/10.1007/s11926-009-0022-4