A new species, Centaurea osmaniyensis (Asteraceae) was described and illustrated here and is only known from Bahçe district in Osmaniye Province in Türkiye. The species belongs to sect. Cynaroides Bunge and it is closely related to C. regia subp. cynarocephala. The ecology and phenology of new species, descriptions, images, the identification key, seed, pollen micromorphology and the IUCN threat category of the new species were presented. In addition, the geographical distribution of Centaurea osmaniyensis and C. regia subp. cynarocephala were provided