In this paper, we attempt to analyse and compare the magnitudes of destruction caused by natural disasters versus socio-economic-political disasters around the world. To do so, we deploy a multi-disciplinary approach that encompasses history, politics, sociology, and economics (Ruiz Estrada, 2011 and 2017). In the methodological discussion, we propose using quantitative and qualitative methods simultaneously to systematically evaluate different type of disasters. In this context, we propose a new analytical tool: “The General Disasters Final Impact Simulator” (GDFI-Simulator). Finally, we apply the GDFI-Simulator to Africa, America, Asia, Europe and Oceania in the 19th and 20th centuries.