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Mast Cell Anergy: absence of symptoms after accidental re-exposure to amoxicillin/clavulanic acid 3 days after anaphylaxis
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  • Loris Guyénard,
  • Marie Tauber,
  • Sophie Debord-Peguet,
  • Frederic Berard,
  • Audrey NOSBAUM,
  • Florence Hacard,
  • Mariana Castells,
  • Jean-François Nicolas
Loris Guyénard
Universite Claude Bernard Lyon 1

Corresponding Author:loris.guyenard@chu-lyon.fr

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Marie Tauber
Universite Claude Bernard Lyon 1
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Sophie Debord-Peguet
Universite Claude Bernard Lyon 1
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Frederic Berard
Universite Claude Bernard Lyon 1
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Audrey NOSBAUM
Universite Claude Bernard Lyon 1
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Florence Hacard
Universite Claude Bernard Lyon 1
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Mariana Castells
Brigham and Women's Hospital
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Jean-François Nicolas
Universite Claude Bernard Lyon 1
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Abstract

Empty Mast Cell Syndrome, also named Post Anaphylaxis Mast Cell Anergy (PAMA), is a temporary state of loss of mast cell responsiveness after a severe immediate hypersensitivity reaction. We describe a case of PAMA after accidental re-exposure to amoxicillin in a patient who developed severe anaphylaxis to this drug three days earlier in the operating room.