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Plant-based anticancer compounds with a focus on breast cancer
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  • Amin Moradi Hasan-Abad,
  • Ali Sobhani-Nasab,
  • Amir Atapour,
  • Hossein Motedayyen,
  • Reza ArefNezhad
Amin Moradi Hasan-Abad
Kashan University of Medical Sciences
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Ali Sobhani-Nasab
Kashan University of Medical Sciences
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Amir Atapour
Shiraz University of Medical Sciences
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Hossein Motedayyen
Kashan University of Medical Sciences

Corresponding Author:hmotedayyen@gmail.com

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Reza ArefNezhad
Shiraz University of Medical Sciences
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Abstract

Cancer as a terrible disease ranks among the most important healthcare issues confronting humanity, necessitating a proactive approach to treatment. Numerous signaling cascades are involved in the complex process of carcinogenesis. Despite its success, chemotherapy has had some undesirable side effects. Plants offer a rich source of novel substances and represent an exciting new option for cancer research. Plants and plant-derived products are revolutionizing themselves because they are less poisonous, quicker, cheaper, safer, and simpler than standard treatment procedures. Natural products are viewed as viable candidates for the creation of anticancer medicines because of their pleiotropic effects on target events in a variety of ways. The actions of plant-derived products are selective; they damage cancer cells and have no significant effect on healthy cells. Several researches are being conducted on the production of potential candidates from these plant-derived products that can stop or inhibit cancer cell proliferation without causing adverse effects. Numerous plant-derived products and the analogs from which they were derived have been identified as potential anticancer therapeutic possibilities. In this review, we summarize research on botanical products with significant and active anticancer activity and their anticancer constituents, with a focus on breast cancer. This review sought to highlight the most recent advances and key successes in plant-derived products and cancer therapies focusing on nuclear and cellular structures. Furthermore, cancer drugs and their problems are discussed.
18 Oct 2023Submitted to Cancer Reports
21 Oct 2023Submission Checks Completed
21 Oct 2023Assigned to Editor
25 Oct 2023Review(s) Completed, Editorial Evaluation Pending
28 Oct 2023Reviewer(s) Assigned
12 Feb 2024Editorial Decision: Revise Major
22 Mar 20241st Revision Received
06 Jun 2024Review(s) Completed, Editorial Evaluation Pending
11 Jul 20242nd Revision Received
24 Jul 2024Submission Checks Completed
24 Jul 2024Assigned to Editor
24 Jul 2024Review(s) Completed, Editorial Evaluation Pending
24 Jul 2024Reviewer(s) Assigned
11 Aug 2024Editorial Decision: Accept