Figure 3: PFD and BIBF mitigated lung fibrosis in silicosis
mice. (A) Representative images of Masson’s trichrome staining in the
crossed lung sections from each group of mice. Statistic graph was
indicated on the right. mRNA levels of FN-1 (B) andCol-I (C) of murine lung tissues. (D)Immunoblots showing the relative protein expression of FN-1, COL-I
compared with β -actin. (E) Statistic graph of FN-1 in
Figure 1D. (F) Statistic graph of COL-I in Figure 1D.(G) Hydroxyproline content of murine lung tissues. Bar values
were shown as the mean ± SE. ∗ denotes the group compared to Si group.
∗P < 0.05, and ns indicates no significance. The range
of P -values for ∗ and # is identical.