Figure 8: Combined therapy of PFD and BIBF improved capacity to limit fibrosis progression compared to monotherapy. (A) Representative images of Masson staining in the crossed lung sections from each group of mice. (B) Statistic graph of Figure 8A. mRNA levels ofFN-1 (C) and Col-I (D) . (E)Immunoblots showing the relative protein expression of FN-1, COL-I compared with β -actin. (F) Statistic graph of FN-1 in Figure 8E. (G) Statistic graph of COL-I in Figure 8E.(H) Hydroxyproline content of murine lung tissues. Bar values were shown as the mean ± SE. ∗ denotes the group compared to Si group. ∗P < 0.05, and ns indicates no significance. The range of P -values for ∗ and # is identical.