Association between the number of live births and aging
The estimated values of FI, ΔKDM-biological age and HD for each pairty
after multiple covariates corrections calculated using a general linear
model are presented in a box plot in Figure 2, which shows the results
of the relationship between the number of live births and biological
aging. As shown in Figure 2 and Supplementary table 4, the estimated FI,
ΔKDM-biological age and HD box charts for two or three live births are
located at the lowest position, while the corresponding box charts for
five or more live births are located at the highest position; and the
corresponding box charts for zero, one, and four live births is located
between these above. In other word, the estimated values of FI,
ΔKDM-bioage and HD adjusted for multiple covariates of mothers with two
or three children were lower, and the correspondings of mothers with
five or more children were higher, comparied with females who had one
children (all P for trend<0.001).