Lesion Set Parameters in Association with AEPVRs
Univariate analysis of the lesion set parameters showed the patients
with AEPVR had a lower impedance drop (P =0.013) including the
regional impedance drop on the posterior wall (P =0.009), lower AI
in the whole left atrium (P =0.039) and the posterior wall
AI(P =0.005)
compared to the patients without AEPVR. Among patients with PVR, AEPVR
group had a lower inter-lesion distance (P =0.003) and a slightly
lower contact force (P =0.057) compared to Gap group
(Supplementary Table 1).
Multivariable logistic regression models were then performed which were
adjusted for all variables showing statistical difference in univariate
analysis or of vital importance in clinical practice. As results, lower
left atrium diameter (P <0.001), lower impedance drop
(P =0.039) and AI (P =0.028) on the posterior wall were
significantly associated with the presence of AEPVR. In patients with
PVR, only a lower inter-lesion distance was independent predictor of
AEPVR (P =0.045)(Table 3).
The ROC analysis was then performed to evaluate the performances between
different prediction index, which demonstrated that the above-mentioned
integrated prediction model for AEPVR containing multiple indicators had
a larger area under curve (AUC=0.790) than single index including
impedance drop, AI and contact force. So was the model established to
predict AEPVR in patients with acute PVR, which also had the largest AUC
of 0.786 (Figure 5).