Note: Proliferation and expansion of Lab-on-a-Chip diagnostic nanosensors in DNA detection is a more specialized function of nanochips or gene and protein microarrays containing markers against the entire human genome to investigate genetic changes.Gene and protein microarrays in very small sizes with the capability of molecular detection based on DNA sequence and human proteins and other pathogenic agents that are used for research purposes. With the proliferation of biological nano sensors and Lab on a chip micro elements, medical diagnostic laboratories are able to examine and measure hundreds of biological substances, from counting blood cells to the detailed examination of blood factors and other body fluids and tissues, pathology laboratories Clinically, various types of imaging systems such as radiology, ultrasound, endoscopy, CT scan, MRI and other specialized diagnostic methods for examining various diseases such as angiography, echocardiography, echocardiography, and other organs are highly developed. Is . With the development of human knowledge in the fields of cellular and molecular sciences, genetics and identification of genes responsible for various diseases, Determining the sequence of the genome of pathogenic agents, checking and comparing them and creating genomic databases, developing molecular diagnostic methods, specialized laboratories using these methods for accurate diagnosis of infectious pathogens, some genetic disorders and even in some cases for prenatal diagnosis. and the possibility of the fetus suffering from severe hereditary diseases and used to determine the gender of the fetus.