Cancer Patients Circadian Rhythm Assessment Based on
Morningness-Eveningness Preference
Ghazal Daftariª, Nasim khajaviradᵇ*, Mahsa
Abbaszadehᵇ, Sahar Karimpour Reyhanᵇ
ªSchool of Medicine, Tehran University of Medical Science, Tehran, Iran.
ᵇDepartment of Internal Medicine, Imam Khomeini Hospital Complex, Tehran
University of Medical Science, Tehran, Iran.
*Corresponding author:
Nasim khajavirad
Address: Department of Internal Medicine, Imam Khomeini Hospital
Complex, Keshavarz Boulevard, Tehran, Iran, Postal Code:1419733141
Email: Ghazall.daftari@gmail.com
Abstract
Background: The circadian rhythm
regulates various physiological processes, including sleep-wake cycle,
cell division and cancer development.
Aims: This study aimed to investigate circadian rhythm patterns in
cancer patients.
Methods and results: In this cross-sectional study, 150 cancer patients
admitted to the internal ward of
Tehran’s Imam Khomeini Hospital
Complex in the fall of 2022 were evaluated. The demographic
characteristics of patients were collected using a checklist. Patients
also completed a morningness-eveningness questionnaire (MEQ). Utilizing
Analysis of Variance (ANOVA) and
Fisher’s exact test, circadian
rhythm types with continuous and categorical variables were compared.
The mean age of the study’s participants was 49.83 ± 14.53 years. A
total of 82.7% (n=124) had non-hematological cancers, and breast cancer
was the most prevalent type of cancer among patients (23.3%). The MEQ
of the patients studied ranged from 41 to 74, with a mean score of 56.6
± 6.34.
Conclusion: According to the findings of this study, the circadian
rhythm is distributed normally among the participants.
Keywords: Cancer, Circadian Rhythm, MEQ, Chronotype,
clock genes