3.4.3 |Studies that include Bos d 5
The available evidence comes from eight studies providing information on
the composition of Bos d 5[30-33, 35-38]. Overall,
six studies showed high specificity (0.91-0.98) at different AUCs
(0-1.94) with different sensitivities (0.24-0.82). In contrast,
Uncuoglu[38] showed high sensitivity (1.0) and
lower specificity (0.7), while Franco[35] showed
lower diagnostic efficacy with sensitivity and specificity of 0.7 and
0.58, respectively.
The research conducted by Alessandri and Hawi[30,
31] has demonstrated that the diagnostic accuracy of various
detection equipment can vary significantly. In Alessandri’s
study[31], the sensitivity and specificity of
ImmunoCAP were found to be 0.90 and 0.50, respectively. However, when
the
Table 2 Summary DTA measures of CRD components tested by allergy
component
ISAC test was used, the sensitivity and specificity were 0.40 and 0.94,
respectively. In Hawi’s study[30], the ImmunoCAP
assay, when used, showed high specificity (0.90-0.93) and low
sensitivity (0.40-0.47); sensitivity was (0.65-0.78) and specificity
(0.66-0.80) when using 3gAllergy assay.