A document by Sneha Shrestha. Click on the document to view its contents.

Author DetailsSneha Shrestha1, Uttam Laudari2, Bimas Payangu2, Bala Ram Malla2, Inesh Khanal1Sneha Shrestha, S., Shrestha, Patan Hospital, Lalitpur, NepalEmail: snehashrestha091@gmail.comORCid: 0000-0002-5575-7882Uttam Laudari, U., Laudari, Department of Surgery, Kathmandu University School of Medical Sciences, Dhulikhel, 45210, NepalEmail: youttam@hotmail.comBimas Payangu, B., Payangu, Department of Surgery, Kathmandu University School of Medical Sciences, Dhulikhel, 45210, NepalEmail: subbabimas30@gmail.comBala Ram Malla, B., Malla, Department of Surgery, Kathmandu University School of Medical Sciences, Dhulikhel, 45210, NepalEmail: mallabr504@yahoo.comInesh Khanal, I., Khanal, Patan Hospital, Lalitpur, NepalEmail: std.ineshkhanal@pahs.edu.npORCid: 0009-0006-1377-3362Corresponding Author :Inesh Khanal, I., Khanal, Patan Hospital, Lalitpur, NepalEmail: std.ineshkhanal@pahs.edu.npORCid: 0009-0006-1377-3362Abstract

A document by Abhyuday Kumar Yadav. Click on the document to view its contents.

Williams-Campbell Syndrome: An unusual case presentation.  Corresponding author :1. Bikram Yadav, bikramyadav123@gmail.com, Dhulikhel Hospital, Dhulikhel, NepalORCiD ID: 0009-0008-0667-7502

Varicella Zoster is a neurotropic virus which leads to acute varicella or it may lay dormant in the spinal root ganglion. Reactivation of varicella zoster causes Herpes Zoster (HZ) and occurs commonly in immunosuppressed conditions like COPD. Severity of Herpes Zoster is also higher among those with comorbidities like COPD. Even among COPD patients, the severity of HZ is said to be higher among those using oral corticosteroids than those using inhaled steroids due to greater immunosuppressive effect. It has also been found that incidence rate of COPD exacerbations, transient ischemic attack and stroke are higher among COPD patients with HZ compared to those without HZ. Herpes zoster vaccinations prevent reactivation of latent HZ and reduce the associated complications. Live attenuated and recombinant vaccines are available for vaccination among which recombinant vaccine is found to be more effective. The cost burden due to HZ among COPD patients was also higher compared to those without HZ. Childhood varicella vaccination is cost effective, however cost effectiveness of adolescent vaccination is unclear.

A document by Abhigan Shrestha. Click on the document to view its contents.