Abbreviations:
AGS = Aicardi Goutières syndrome; ARRIVE= Animal Research: Reporting ofin vivo Experiments; BBB = Blood brain barrier; CCI = Controlled
cortical impact; c-di-GMP = Bis-(3’-5’)-cyclic dimeric guanosine
monophosphate; cGAMP = Cyclic adenosine monophosphate guanosine
monophosphate; cGAS = Cyclic guanosine monophosphate AMP synthase; Ct =
Cycle threshold; CX3CR1 = C-X3-C motif chemokine receptor 1; CXCL10 =
C-X-C motif chemokine ligand 10; DAMP = Danger associated molecular
pattern; DAPI = 4’,6-diamino-2-phenylindole; ER = Endoplasmic reticulum;
ERIS = Endoplasmic reticulum interferon stimulator; HRP = Horseradish
peroxidase; IFNAR = Interferon alpha and beta receptor subunit; IKK =
IκB kinase; IRF3 = Interferon regulatory factor 3; MITA = Mediator of
IRF3 activation; OCT = optimal cutting temperature; PERK = Protein
kinase R-like ER kinase; PFA = Paraformaldehyde; PVDF = Polyvinylidene
fluoride; RARE = rapid acquisition, relaxation enhanced ; RIPA =
Radioimmunoprecipitation; SAH = Subarachnoid haemorrhage; SDS = Sodium
dodecyl sulphate; SLE = Systemic lupus erythematosus; STING = Stimulator
of interferon genes; TBI = Traumatic brain injury; TBS = Tris-buffered
saline; TBK1 = Tank binding kinase 1; TBST = Tris-buffered saline-tween;
TMEM173 = Transmembrane protein 173