Blood vessels are an important part of the human circulatory system [1-4]. In clinical surgery, the common method for treating ruptured blood vessels is suturing, but this method can cause inflammatory reactions [5-6]. With the popularization of lasers, they have been widely used in the medical field. However, due to the poor absorption of laser energy by tissues, the tensile strength of tissues after joining is low. To further improve the tensile strength after laser joining, this study analyzed the law of the effect of pre-dressing-assisted laser on the tensile strength and thermal denaturation of vascular tissues after joining with different components and concentrations by designing experiments. The experimental results showed that the tensile strength of the joined tissues could reach 50.978 KPa, and the degree of thermal denaturation was only 0.025, which is of great significance for the study of laser-joined vascular tissues.

Considering difficulties of achieving vertical incidence of beam in different positions of skin, it’s significant to study potential effects of incidence angles of laser on incisions. Surgical platform with a 1064nm continuous fiber laser was established. Incident angle was adopted and real-time temperature fluctuations in laser operating area could be monitored. The rats were treated with laser at day 0 and day 3 after incision modeling, and H&E, Masson, Sirius Red and Immuno-histochemical staining and enzyme-linked immunosorbent assay were adopted at day 3,7,14 to analyze the performance of healing. Laser with energy density of 67.54J/mm 2 can effectively accelerate wound healing in vivo, in which laser with incident angle around 60° can effectively avoid scar hyperplasia. Therefore, the use of low energy laser with small deflection angle has a good clinical application prospect in promoting wound healing.