not-yet-known not-yet-known not-yet-known unknown Introduction Dowling Degos disease (DDD) is a rare, progressive, autosomal dominant disorder characterized by symmetrical, pigmented macules involving the axillae, groins, face, neck, arms and trunk as well as scattered comedo- like lesions and pitted acneiform scars.1 Its prevalence is unknown.DDD was described initially by Dowling and Freudenthal in 1938.2 Typically the onset of DDD is after puberty and commonly occurs in the third to fourth decade of life.3 Women are more affected than men.2 Histopathology of skin lesion is diagnostic. We, hereby report a family having DDD with one of the offspring showing features of downs syndrome.