3.2 Ferroptosis and atrial fibrillation
Atrial fibrillation (AF) is an important risk factor for AIS, resulting
in a five-fold increased risk of stroke and two-fold increased
mortality77. Atrial fibrillation (AF) is also one of
the most common preventable causes of AIS and is often associated with
cardiogenic stroke. Compared with other ischemic stroke subtypes,
cardiogenic stroke is associated with more severe severity, poorer
prognosis, and a relatively higher recurrence rate78.
Therefore, understanding the pathogenesis of atrial fibrillation and
selecting appropriate drugs based on the pathological mechanism may
greatly help the treatment and prognosis of patients with cardiogenic
stroke.