Mechanical intravascular hemolysis can occur after cardiac artificial prosthesis implantation. With the development of medical technology and the improvement of valve design, the incidence of severe mechanical hemolysis after surgery has been significantly reduced, but it cannot be completely avoided. At the same time, subclinical hemolysis after surgery is common but often ignored. With the extensive development of cardiac interventional surgery, the issue of postoperative hemolysis deserves further attention. Ultrasound can effectively evaluate cardiac artificial prosthesis implantation and provide imaging evidence for predicting and diagnosing postoperative hemolysis. This article introduces and explores the latest progress in applying echocardiography parameters in mechanical hemolysis after cardiac artificial prosthesis implantation.