Detection of clinical samples
A total of 93 blood samples were collected from the First Affiliated Hospital of Xiamen University. All samples were detected by RPCR-MC in an extraction-free manner. The results were consistent with the results of Sanger sequencing, as shown in Table S4. Figure 8 illustrates that CYP2C19 * 2 heterozygosity and wild-type account for a relatively high proportion of the Chinese population, with homozygous mutation being relatively rare. CYP2C19 * 3 wild-type accounts for a relatively high proportion of the population tested, heterozygosity was less common, and mutation was the least common. CYP2C19 * 17 mostly comprised wild-type, with mutant and heterozygosity being almost absent. These results indicate that the polymorphism ratio of each locus in the Chinese population is roughly consistent with previous research results.