Figure 3. Top pathways and interactome represented by DEGs in Srsf1-ko mice and SLE patients reveal pathways in lymphocyte activation, cytokine signaling and interferon response.

A . and B . Metascape heatmap graphs show the top pathways associated with the upregulated and downregulated DEG inSrsf1 -ko mice (A ) and SLE patients (B ). Network analysis on the right shows interactome represented by the DEGs.