Figure 4. SRSF1 controls genes involved in T cell cytokine production/signaling and differentiation which are aberrantly regulated in SLE.
Pathway enrichment analysis of overlapping DEGs from CD4 T cells fromSrsf1 -ko mice and SLE patients was performed in Metascape. Graphs show the top pathways represented by the DEGs that overlap between. Network analysis on the right shows interactions between DEGs and thickness of connecting lines indicates strength of interactions.