OPTI-CLOT study group
OPTI-CLOT/To WiN study group aims to implement personalized treatment bypharmacometric-guided dosing of factor concentrates, desmopressin and non-factor therapies in patients with bleeding disorders.
OPTI-CLOT/ To WiN Steering Committee, the Netherlands: M.H. Cnossen (principal Investigator & chair OPTI-CLOT-To WiN) and R.A.A. Mathôt (co-investigator). F.W.G. Leebeek, Rotterdam; , M. Coppens K. Fijnvandraat, Amsterdam; K. Meijer, Groningen, S.E.M. Schols, Nijmegen; H.C.J. Eikenboom, Leiden; R.E.G. Schutgens, Utrecht; F. Heubel-Moenen, Maastricht; L. Nieuwenhuizen, Veldhoven; P. Ypma, The Hague; M.H.E. Driessens, Nijkerk.
Trial bureau: I. van Vliet, Rotterdam.
Local collaborators the Netherlands : M.J.H.A. Kruip, S. Polinder, Rotterdam; P. Brons, Nijmegen; F.J.M. van der Meer, Leiden; K. Fischer, K. van Galen, Utrecht
Principal investigators and local collaborators in the United Kingdom: P. W. Collins, Cardiff; M. Mathias, P. Chowdary, London; D. Keeling, Oxford.