\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{CJKutf8} 
\usepackage[utf8]{inputenc}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[greek,english]{babel}



\usepackage{float}








\begin{document}
\begin{CJK}{UTF8}{gbsn}

\title{Science AMA Series: We are researchers at Johns Hopkins. We have just
developed a new kind of noninvasive probe that visualize living cells in
real time and we are here today to talk about it. AMA!}



\author[1]{HopkinsMedicine_AMA }%
\author[1]{r/Science AMAs}%
\affil[1]{Affiliation not available}%


\vspace{-1em}



  
  \date{April 23, 2026}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
Hi Reddit, we are Xingde Li
(https://www.hopkinsmedicine.org/profiles/results/directory/profile/0800034/xingde-li),
professor of Biomedical Engineering and Wenxuan Liang, a postdoctoral
fellow at Johns Hopkins Medicine majoring in biophotonics. Our lab works
to improve endomicroscopy in the hopes of someday diminishing our
dependencies on biopsies. We have recently developed two new endoscopic
probes that have a potential to significantly improve imaging
diagnostics. Our first probe uses the same basics from the two-photon
microscope but in a much smaller footprint. Our prototype probe, 2mm in
diameter, takes advantage of the cell's own ability to glow and
eliminates the need for traditional fluorophores -- usually harmful to
the human body. This allow us to directly visualize fine structural
changes and monitor cell activity in vivo and in real time at histology
level but without the need for tissue removal.
(https://www.nature.com/articles/lsa201782) Our second probe is even
smaller (approximately 500 \selectlanguage{greek}µ\selectlanguage{english}m in diameter) but offers us about four
times higher resolution than other currently used devices. The small
probe size eases the delivery of endoscope to small areas of the body.
This can greatly reduce patient's discomfort during the endoscopy
procedure while also providing a high resolution and clear visualization
of tissue microstructures. This is very important for detecting disease
at early stages when tissue microstructural changes are subtle and the
disease is still at a manageable stage.
(https://www.nature.com/articles/s41467-017-01494-4 ) We will be back at
1pm ET today to answer your questions.%
\end{abstract}%



\sloppy




\selectlanguage{english}
\FloatBarrier
\end{CJK}\end{document}

