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\title{Science AMA Series: Neil Brown here to talk about how fungal pathogens
sense the `touch and taste' of their plant hosts and if this can this be
used to fight crop disease. AMA!}



\author[1]{Dr_Neil_Brown }%
\author[1]{r/Science AMAs}%
\affil[1]{Affiliation not available}%


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  \date{April 24, 2026}


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\begin{abstract}
Hello Reddit! I'm Neil Brown, a fungal biologist and a BBSRC Future
Leader Fellow at Rothamsted Research in the UK. In my school leavers
book, my friends were asked ``What will Neil end up doing?'' They
answered ``saving trees'', to which I laughed. But it appears that they
knew more about me than I did, as I now devote my days to understanding
plant diseases, contributing to the knowledge and innovation needed to
develop new ways to protect our crops. New approaches to control fungal
diseases that threaten our food security and health, through the
contamination of crops with harmful toxins, are urgently needed. To
achieve this, I am asking: how does a fungal pathogen landing on a plant
decide if it is a suitable host; how does it know where to infect or
where to find the best source of food; and how does it know when to
deploy different virulence strategies, such as the secretion of toxins
or hydrolytic enzymes? These are the questions I hope to answer in my
study of fungal `touch and taste' receptors, similar to those found on
our tongue. I will focus on Fusarium, a fungal pathogen that cause
disease on wheat, barley, rice and maize. The goal is to determine
whether these fungal `touch and taste' receptors are biological targets
that can potentially be drugged to prevent a pathogen from causing crop
diseases and toxin contamination. It would be great to discuss my
research with you. So go ahead. Ask me anything. I will be back at 11am
ET (4pm BST). In the meantime, you are welcome to find out more about
me, and my international experiences as an early career researcher, in a
blog entry I recently wrote for Rothamsted Research's `A day in the life
of a Research Scientist' blog series
(http://www.rothamsted.ac.uk/day-life-dr-neil-brown). Hi everyone! Thank
you all for this broad range of interesting questions. I will check back
later to answer a any I missed. All the best, Neil%
\end{abstract}%



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