\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{CJKutf8} 
\usepackage[utf8]{inputenc}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}
\begin{CJK}{UTF8}{gbsn}

\title{Science AMA Series: I'm Nicholas Katsanis, a human geneticist at Duke,
let's have a conversation about human genetic disorders: facts, dreams,
and most definitely the eradication of unicorns, AMA!}



\author[1]{Dr_Nico_Katsanis }%
\author[1]{r/Science AMAs}%
\affil[1]{Affiliation not available}%


\vspace{-1em}



  
  \date{April 23, 2026}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
Greetings from sunny Greece, where I am taking a few hours to chat with
you about human genetics on reddit. My name is Nicholas Katsanis, but
please call me Nico. I am a human geneticist, and the Director of the
Center for Human Disease Modeling at Duke University. My passion has
always been to understand human genetic disorders all the way from the
discovery of genes that cause them to dissecting pathomechanism and
thinking about the possibility of developing new therapies. Over the
years, my team and I have worked to identify genes that cause a range of
disorders, with an emphasis on rare pediatric traits. As part of that
journey, we have begun to appreciate how the context of the genome can
alter the impact of deleterious mutations and impact clinical outcomes
profoundly. In that context, we have also realized how the complexity of
the genome poses a real challenge in understanding pathomechanism as
well as predicting outcomes for patients; we are working hard to develop
new biological tools that can help us interpret the functional
consequence of genetic variation. In parallel, we are working to build a
path towards integrating the research and the clinical enterprise as a
way to improve the impact of genetics in health care. Today, I am happy
to field any and all questions about human genetics, from why Mendel's
peas are truly wrinkly to what the major stumbling blocks are to really
accelerating the development of therapeutics. I'll be back at 1 pm ET
(10 am PT, 6 pm UTC) to answer your questions, ask me anything!%
\end{abstract}%



\sloppy




\selectlanguage{english}
\FloatBarrier
\end{CJK}\end{document}

