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\title{Science AMA Series: I'm Ying-Hui Fu, I study the genetics of sleep at
UCSF. My lab discovered a gene that makes some people more efficient
sleepers, needing only 4-6 hours per night. AMA!}



\author[1]{Ying-Hui_Fu }%
\author[1]{r/Science AMAs}%
\affil[1]{Affiliation not available}%


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  \date{April 23, 2026}


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\begin{abstract}
There are two things I consider more important than sleep: air and
water. We spend more time sleeping than engaging in any other single
activity, but we know very little about how day-to-day sleep behavior is
regulated. My lab uses human genetics to gain a better understanding on
this topic. We've found that sleep behavior is heavily influenced by our
genetic makeup. Just like many other traits --- height, weight, body
shape --- sleep behavior is at least partly inherited. In 2009, we
discovered a mutation in the DEC2 gene that allows some people to sleep
only four to six hours a night and feel completely refreshed. We study
such efficient sleepers in hopes to understand why sleep is so
important! Ask me anything about how genes affect sleep and why we need
to pay attention to sleep! Here's my lab at UCSF Here's a recent UCSF
article about the impact of sleep-deprivation: Short Sleepers Are Four
Times More Likely to Catch a Cold Here's a BBC article about the sleep
gene, The People Who Need Very Sleep I will be back at 1 pm ET (10 am
PT, 5 pm UTC) to answer your questions, AMA! EDIT: Good morning
everyone. Thanks for all the great questions and lets get to the
answers! EDIT: Thanks for all the great questions. I enjoyed it very
much. I am signing off!%
\end{abstract}%



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