Diabetes mellitus (DM) commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period. Diabetes mellitus is the most common endocrine disorders affecting million people worldwide. It is a chronic condition, characterized by hyper-glycemia, due to impaired insulin secretion. It is a disease that affects the body ability to produce or use of insulin. Insulin is a hormone. When the body turns the food you eat into energy (sugar or glucose), insulin is released to help transport this energy to the cells. Its chemical message tells the cell to open and receive glucose. If the insulin produce is little or no production, leads too much sugar remains in your blood (hyper glycaemia). Blood glucose levels are higher than normal for individuals with diabetes. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of various organs, especially the eyes, kidneys, nerves, heart and blood vessels. [1]