Little information exists about the perspective behaviour of physicians and the misuse of anti- diabetic drug.

The clinical study i.e.; drug utilization of anti-diabetic drug used in diabetes is carried out for the first time at inpatient and outpatient department of INTEGRAL UNIVRSITY HOSPITAL, LUCKNOW.

In our study, it was observed that over 350 persons (suffering from various diseases) visited the inpatient department of IU Hospital over a period of 6 months. 100 patients, on the basis of inclusion and exclusion criteria, were selected for the present study.

Demographic characteristics showed that percentage of males suffering from diabetes was more than females. It was observed that among them (male and female) 44% were male and 56% were females. Studies showed that females are more persistent diabetic as compared to males; the major reason might be due to the occupational reasons.

Further, it was found that a majority of the patients who were having a diabetes were in the age group of 50-70 years and the lowest % was in less than 30 years of age groups.

In this drug utilization study, 100 prescriptions were analyzed. A total of 195 antidiabetic drugs prescribed, of which 37.90 % wereBiguanides , 22.60 % sulphonylureas , 25.64 % wereinsulin . DPP-4 Inhibitors were 7.20%, 1.02% werethiazolidinediones (PPARγ activator) and 5.64% wereα-Glucosidase inhibitors. Most of the anti- diabetic prescribed were from the essential medicine list.

During the study, it was observed th at most frequently prescribed antibiguanides insulin and sulphonylureasdiabetic drug classes were and the most frequently prescribed anti monotherapy among them is Biguanides .

Overall 9 ADRs were reported during the study (table 6.8). Hypoglycemia was the most common ADR observed in 04 patients (moderate intensity in 2 patients and mild in one patient). Whereas gastric irritation occurs in 02 patients and abdominal discomfort occurs in 03 patients, among which 6 patients were males and 3 patients were found to be female. The percentages of ADR distribution among genders were found to be 66.66% in males and 33.33% in females. Among all 9 ADRs, 3 cases of mild (33.33%), 4 cases of moderate (44.44%), and 2 cases of severe (22.22%) types of ADRs were detected.