loading page

Green Oxidation of Isochromans to Isochromanones with Molecular Oxygen Catalyzed by A Tetranuclear Vanadium Cluster
  • +3
  • Huixin Huang,
  • Baokuan Chen,
  • Yiru Fu,
  • Jing Sun,
  • Yanfeng Bi,
  • Mingdong Zhou
Huixin Huang
Liaoning University of Petroleum and Chemical Technology
Author Profile
Baokuan Chen
Liaoning University of Petroleum and Chemical Technology
Author Profile
Yiru Fu
Liaoning University of Petroleum and Chemical Technology
Author Profile
Jing Sun
Liaoning University of Petroleum and Chemical Technology
Author Profile
Yanfeng Bi
Liaoning University of Petroleum and Chemical Technology
Author Profile
Mingdong Zhou
Liaoning University of Petroleum and Chemical Technology

Corresponding Author:mingdong.zhou@lnpu.edu.cn

Author Profile

Abstract

Isochromanone is the core structure of many bioactive compounds. Direct oxidation of isochromans is one of leading methods for the construction of isochromanones, while most established processes remain suffering from the use of environmental unfriendly metal oxidants, harsh reaction conditions, and the difficulty in catalyst recycling and production separation. Herein, we report a convenient, cost-effective, and green method for the synthesis of high-value added isochromanones via isochroman oxidations with O2 by a novel heterogeneous vanadium cluster catalyst (Cat.1) under mild conditions. This reaction protocol demonstrates high catalytic activity with good catalyst recyclability and reusability for a wide scope of substrates.
20 Mar 20231st Revision Received
22 Mar 2023Submission Checks Completed
22 Mar 2023Assigned to Editor
22 Mar 2023Review(s) Completed, Editorial Evaluation Pending
23 Mar 2023Reviewer(s) Assigned
05 Apr 2023Editorial Decision: Accept