Human papilloma virus vaccines
HPV vaccines may contain residues of yeast. Individuals with a history
of severe allergy to yeast could theoretically experience a severe
allergic reaction after administration of this
vaccine45. Therefore, in case of yeast allergy, it is
recommended to perform a complete allergy evaluation.
Some brands of HPV vaccines contain PS80 as stabilizer, which might be
responsible for hypersensitivity reactions46. Children
that experienced a severe allergic reaction to this substance should be
vaccinated with formulations that do not contain PS80 or should be
addressed to a specialized allergy center to perform skin tests and
prescribe the protocol of vaccination as described in the diagnostic
work-up.