Key Messages
- Chemotherapy ototoxicity is a well known adverse effect that has few
treatment options and that has not been sufficiently studied in the
adult population.
- Tinnitus and vertigo are distressing symptoms overlooked in
cisplatin-induced ototoxicity research.
- Pharmacological interventions to prevent cisplatin induced hearing
loss are controversial given their mild efficacy and potential side
effects. Future investigations of sodium thiosulfate for preventing
cisplatin-induced ototoxicity are warranted.