Diffuse alveolar hemorrhage (DAH) is a clinical condition characterized by bleeding into alveolar space as a result of vascular or capillary injuries. There are three types of DAH based on the process that causes blood spillage including diffuse hemorrhage associated with vasculitis, bland hemorrhage (without vasculitis) and diffuse with another process (such as tumor). Drug induced DAH is a type of bland hemorrhage results from overreaction to various drugs. Ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) used for pain alleviation at the range of opioid level. Hypersensitivity reactions due to NSAIDs usage is common and up to 20% in high risk people. In this article we report a case of DAH due to IV ketorolac prescription.