In this paper, the model of information exchange system was promoted. With Miner's linear cumulative damage theory and life prediction method, the fatigue strength of Hinge Sleeve of Cubic was calculated and simulated by ANSYS. Firstly, the model of Hinge Sleeve of Cubic is established, and the stress of the Hinge Sleeve of Cubic is calculated. Then the fatigue strength of Hinge Sleeve of Cubic was calculated with Miner's linear cumulative damage theory and life prediction method. In ANSYS, combined with static analysis, topology optimization and Fatigue function corresponding data, the information exchange system for life optimization design of Hinge Sleeve of Cubic was created. According to the required load conditions, the material foundation data and boundary constraints are set, and the stress correction curve is loaded for fatigue calculation. With the results of fatigue calculation, the simulation verification is carried out again. The final model of mass-reduction design is obtained through repeated optimization verification by combining ANSYS data with topology optimization. Compared with traditional theoretical calculation methods, the optimized Hinge Sleeve of Cubic was obtained by the optimization method based on information exchange model proposed, it has better computing performance. The simulation results show that the working performance of the optimized Hinge Sleeve of Cubic meets the design requirements.