Variables collected:
Data were collected regarding demographics (age, sex, and sickle cell
genotype), reason for hospitalization (vaso-occlusive pain crisis, acute
chest syndrome [ACS], fever, COVID-19, and others), ICU admission
andlength of hospitalization..
With respect to VTE, the index VTE date was defined as the date when the
imaging study identified the VTE. Data were collected on the type (DVT,
CSVT, and PE) and location of the thrombotic event (e.g., cerebral
veins, upper or lower extremity), any thromboembolic complication,
choice of anticoagulant, mechanical thrombectomy or thrombolysis.
Additionally, charts were reviewed for presence of traditional risk
factors for thrombosis including central venous catheter (CVC), family
or personal history of thrombosis, cardiac comorbidity, obesity, use of
estrogen-containing oral contraceptive pills, recent surgery within the
past 30 days14–16, Factor V Leiden gene mutation,
prothrombin gene mutation, deficiency of protein C, S and/or
antithrombin, and presence of antiphospholipid antibodies.