Variables collected:
Data were collected regarding demographics (age, sex, and sickle cell genotype), reason for hospitalization (vaso-occlusive pain crisis, acute chest syndrome [ACS], fever, COVID-19, and others), ICU admission andlength of hospitalization..
With respect to VTE, the index VTE date was defined as the date when the imaging study identified the VTE. Data were collected on the type (DVT, CSVT, and PE) and location of the thrombotic event (e.g., cerebral veins, upper or lower extremity), any thromboembolic complication, choice of anticoagulant, mechanical thrombectomy or thrombolysis. Additionally, charts were reviewed for presence of traditional risk factors for thrombosis including central venous catheter (CVC), family or personal history of thrombosis, cardiac comorbidity, obesity, use of estrogen-containing oral contraceptive pills, recent surgery within the past 30 days14–16, Factor V Leiden gene mutation, prothrombin gene mutation, deficiency of protein C, S and/or antithrombin, and presence of antiphospholipid antibodies.