Patient characteristics
Fourteen patients received VDC-ICE therapy as described in Table 1. The
median age at diagnosis was 1.7 years (range=0.1-10.5), and 50% were
male (n=7) and 79% Caucasian (n=11). The most common diagnosis was
non-kidney MRT (n=7), followed by DAWT (n=3), MRT of the kidney (n=2),
CCSK (n=1), and anaplastic chordoma (n=1). Six patients had metastatic
disease (stage IV), with the kidney (n=6) or soft tissue (n=6) being the
most common primary disease sites. Five patients received previous
treatment, and 6 patients underwent complete or partial nephrectomy
prior to chemotherapy.