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Paraneoplastic encephalitis as a rare paraneoplastic syndrome of adrenocortical carcinoma: A rare case report.
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  • Debabrata Mohapatra,
  • Madhavi Tripathi,
  • Sakshi Ojha,
  • Kritika Setlur,
  • Jagdish Meena,
  • Rachna Seth,
  • Aditya Gupta,
  • Biswaroop Chakrabarty,
  • Sheffali Gulati
Debabrata Mohapatra
All India Institute of Medical Sciences Department of Pediatrics
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Madhavi Tripathi
All India Institute of Medical Sciences
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Sakshi Ojha
All India Institute of Medical Sciences Department of Pediatrics
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Kritika Setlur
All India Institute of Medical Sciences Department of Pediatrics
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Jagdish Meena
All India Institute of Medical Sciences Department of Pediatrics

Corresponding Author:drjpmeena@yahoo.com

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Rachna Seth
All India Institute of Medical Sciences Department of Pediatrics
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Aditya Gupta
All India Institute of Medical Sciences Department of Pediatrics
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Biswaroop Chakrabarty
All India Institute of Medical Sciences Department of Pediatrics
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Sheffali Gulati
All India Institute of Medical Sciences Department of Pediatrics
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Abstract

Paraneoplastic neurologic syndromes (PNS) are rare in pediatrics and are understood to be consequences of cross-reactivity against various neuroendocrine antigens expressed on cancer cells. Here, we report a case of autoimmune encephalitis, a type of paraneoplastic neurologic syndrome that was associated with a case of adrenocortical carcinoma and had some clinical response to immunosuppressive therapy. Adrenocortical carcinoma is a rare tumor with controversial tissue of origin but expresses various neuroendocrine antigens that could be the possible mechanism for this rare yet interesting association.