Noise and light levels during hospitalizations can disrupt sleep and circadian health, resulting in worse health outcomes. This study describes patterns of noise and light in an inpatient room of children undergoing stem cell transplants. Objective meters tracked noise and light levels every minute for 6 months. Median overnight sound was 55dB (equivalent to conversational speech), which exceeded recommendations. There were 3.4 loud noises (>80dB) per night on average. Children spent 62% of the 24-hour cycle in non-optimal lighting, with daytime light dimmer than recommended 98% of the time. These data suggest improvements for hospital environment in pediatric cancer patients.