Running title:- Effect of gene and homocysteine.Authors:- Neetu Kataria1, Vasantha C. Kalyani21 Ms. Neetu Kataria, Ph. D. Scholar, AIIMS, Rishikesh, Uttarakhand, India, neetukataria31@gmail.com, ORCID-0000-0002-0956-5361, h-index=3, citations=172 Prof. Vasantha C. Kalyani, Professor and Principal, Department of Nursing, AIIMS, Deoghar, Jharkhand, 0000-0003-1075-9208, vasantharaj2003@gmail.com, h-index=5, citations=102